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Here is a new book on methods and issues in clinical research. Its objectives can be summarized in three points. 1. Integrate medical and statistical components of clinical research. 2. Do justice to the operational and practical requirements of clinical research. 3. Give space to the ethical implications of methodological issues in clinical research. The book ends with a brief description of the drug development process and the phases of clinical development. Product details Format Hardback | 343 pages Dimensions 155 x 235 x 27.9...

This manual is part of a series of resources for improving the quality of care for severely ill children in health facilities. It supports the improved use and availability of oxygen therapy in low resource settings. The manual addresses the need for appropriate detection of hypoxaemia and use of pulse oximetry, oxygen delivery systems and monitoring of patients on oxygen therapy. In addition, the manual addresses practical use of pulse oximetry, and oxygen concentrators and cylinders. Advanced and high technology oxygen options, such as mechanical ventilation or extracorporeal membrane oxygenation, are not described. The main purpose is to: * Increase the awareness and the need for improving the availability of oxygen therapy in low resource settings. * Improve the detection and management of hypoxaemia in severely ill children. * Improve the delivery and monitoring of patients on oxygen therapy. This practical bedside manual can be used in most areas of the world and can be adapted...

"Este tercer volumen del bestseller La biblia de los cristales presenta más de 250 cristales y minerales de nueva generación y alta vibración que te ayudarán en tu proceso sanador y de transformación. Entre ellos se incluyen varios cristales extraordinarios cuyas propiedades esotéricas no figuran en ningún otro texto. En esta guía esencial también incluimos apartados dedicados a las calaveras de cristal, a los seres cristalinos, a las piedras de Madagascar e indicaciones para trabajar con los nuevos chakras tales como la Estrella del Alma y los chakras de la Manifestación, que resultan estimulados por los poderosos cristales que aparecen en este tomo." Product details Format Paperback | 400 pages ...

Volume 5 of Contemporary Nephrology summarizes major advances in 15 different areas of nephrology. As in previous volumes the different chapters constitute up- of the discipline contributed by individuals dates in both basic and clinical aspects with in-depth expertise in their respective areas. We are grateful to the authors for their outstanding contributions to this fifth volume. Drs. Reuss and Cotton review in Chapter 1 new advances in our understanding of water transport in epithelial tissues responsive to antidiuretic hormone. In Chap- ters 2 and 3 Dr. Knox and Dr. Schoolwerth and their associates summarize respec- tively new information in the areas of renal hemodynamics and electrolyte excre- tion, and renal metabolism. Chapter 4, written by Drs. Laski and Kurtzman, updates recent developments in the regulation of acid-base balance in health and disease. Chapter 5, contributed by Drs. Sutton and Cameron, provides the reader with a detailed account of progress in the area of min...

Providing authoritative, everyday guidance in the diagnosis and management of children with congenital and acquired heart disease, Park's Pediatric Cardiology for Practitioners is the go-to reference of choice for pediatricians, family practitioners, NPs, and PAs-as well as medical students, residents, and fellows. The 7th Edition of this core text comprehensively covers every aspect of pediatric cardiology in an easy-to-read, practical manner for the non-specialist, bringing you completely up to date with all that's new in this fast-changing field. Covers everything from history and physical examination through preventative treatment and the management of special problems. Incorporates all of the latest concepts and most recent developments in pediatric cardiology. Offers highly accessible content through the extensive use of numbered lists, easy-to-use tables, and explanatory graphs and diagrams. Features new chapter outlines, as well as a new larger size and two-color fo...

Winner of the Medical Journalists' Association's Tony Thistlethwaite Award A Finalist for the Royal Society Winton Prize for Science Books Recipient of the International OCD Foundation's Illumination Award What might lead a schoolgirl to eat a wall of her house, piece by piece, or a man to die beneath an avalanche of household junk that he and his brother have compulsively hoarded? At what point does a harmless idea, a snowflake in a clear summer sky, become a blinding blizzard of unwanted thoughts? David Adam--an editor at Nature and an accomplished science writer--has suffered from obsessive-compulsive disorder for twenty years, and The Man Who Couldn't Stop is his unflinchingly honest attempt to understand the condition and his experiences. In this riveting and intimate blend of science, history, and memoir, Adam explores the weird thoughts that exist within every mind and explains how they drive millions of us toward obsession and compulsion. Told with fierce c...

This "profound and disturbing" (New York Times Book Review) bestseller written by a Guantánamo prisoner is now a major feature film starring Tahar Rahim and Jodie Foster. When The Mauritanian was first published as Guantánamo Diary in 2015--heavily redacted by the U.S. government--Mohamedou Ould Slahi was still imprisoned at the detainee camp in Guantánamo Bay, Cuba, despite a federal court ruling ordering his release, and it was unclear when or if he would ever see freedom. In October 2016 he was finally released and reunited with his family. During his fourteen-year imprisonment the United States never charged him with a crime. Now he is able to tell his story in full, with previously censored material restored. This searing diary is not merely a vivid record of a miscarriage of justice, but a deeply personal memoir--terrifying, darkly humorous, and surprisingly gracious. The Mauritanian is a document of immense emotional power and historical importance. ...

Jedes Kind liebt Geschichten. In diesem Buch erzählt ein Hase Lerngeschichten für Kinder ab 5 Jahren.Um ein kreatives Lesevergnügen zu schaffen, ist nach jeder Geschichte ein Feld, wo die Geschichte gemalt werden kann. Die Fantasie wird angeregt und liebevoll bebildert. So ist dieses Büchlein einzigartig in seiner Art!Ich wünsche viel Spaß beim Lesen oder Vorlesen und kreativem Umsetzen der Geschichten.Werfen Sie gern vorher einen Blick ins Buch Product details Format Paperback | 60 pages Dimensions 203 x 254 x 3mm ...

At the start of this brilliantly unconventional family memoir, David Gilmour is an unemployed movie critic trying to convince his fifteen-year-old son Jesse to do his homework. When he realizes Jesse is beginning to view learning as a loathsome chore, he offers his son an unconventional deal: Jesse could drop out of school, not work, not pay rent - but he must watch three movies a week of his father's choosing. Week by week, side by side, father and son watched everything from True Romance to Rosemary's Baby to Showgirls, and films by Akira Kurosawa, Martin Scorsese, Brian DePalma, Billy Wilder, among others. The movies got them talking about Jesse's life and his own romantic dramas, with mercurial girlfriends, heart-wrenching breakups, and the kind of obsessive yearning usually seen only in movies. Through their film club, father and son discussed girls, music, work, drugs, money, love, and friendship - and their own lives changed in surprising ways. ...

For twenty years Dr. Ricki Robinson has been providing hope and help for children with Autism Spectrum Disorders. Her integrative, strengths-based approach to treatment includes a thorough evaluation of your child's medical, developmental, social, emotional, behavioral and educational issues to find the solutions that maximize your child's health and well-being. Autism Solutions gives parents a greater understanding of their child's unique learning, sensory and medical profile. Recognizing that no parent can do this alone, Dr. Robinson explains how to establish a team of professionals who can work with the child to give him or her the opportunity to live well, learn, interact and thrive. Autism Solutions covers a wide range of issues, including: - Helping your child relate, communicate and think - Recognizing and overcoming common health challenges - Effectively treating diseases and disorders that frequently accompany autism - Understanding how behavior can be a form of ...

52 playful and easy to understand activites to hhelp parents teach children moral lessons that they won't forget A child says, I hear and I forget, I see and I remember, I do and I understand. 10-Minute Life Lessons for Kids is a book about seeing and doing--a book that gives parents the ability to teach the powerful principles of honesty, trust, generosity, love, and other values. Children will discover the objectives themselves as they actively participate in fun games and activities. The games can be done in any order, with very little planning and with very few supplies--just common objects most people have around the house like toothpicks, string, pennies, or an apple. Some can be done while riding in the car, and others can be expanded to fill a whole evening with family fun. The activities in 10-Minute Life Lessons for Kids will not only create cozy and enjoyable moments of family togetherness, they will have a lasting impact on your growing child. ...

*THE SUNDAY TIMES BESTSELLER* FROM THE AUTHOR OF EAST WEST STREET As Governor of Galicia, SS Brigadefuhrer Otto Freiherr von Wachter presided over an authority on whose territory hundreds of thousands of Jews and Poles were killed, including the family of the author's grandfather. By the time the war ended in May 1945, he was indicted for 'mass murder'. Hunted by the Soviets, the Americans, the Poles and the British, as well as groups of Jews, Wachter went on the run. He spent three years hiding in the Austrian Alps, assisted by his wife Charlotte, before making his way to Rome where he was helped by a Vatican bishop. He remained there for three months. While preparing to travel to Argentina on the 'ratline' he died unexpectedly, in July 1949, a few days after spending a weekend with an 'old comrade'. In The Ratline Philippe Sands offers a unique account of the daily life of a senior Nazi and fugitive, and of his wife. Drawing on a remarkable archive o...

Following the events of Neighbor Vol.1, we'll see the development of the main characters relationship and will also visit the past of one of them with an extra chapter at the end;) Product details Format Paperback | 146 pages Dimensions 178 x 254 x 10mm | 365g Publication date 04 Jun 2018 ...